i!—

I wanted to stop my

bone loss, but I did more.

I reversed it with BONIVA *

If you have osteoporosis, like me, calcium-rich foods, vitamin D, and exercise can help.

But they may not be enough to keep your bones strong. So ask your doctor if once-monthly

BONIVA can help you do more. Studies show, after a year on BONIVA, 9 out of 10

women stopped and reversed their bone loss.1

And my test results proved I did, too.

BONIVA is a prescription medication to treat and prevent postmenopausal osteoporosis.

Ask your doctor if BONIVA is right for you.

"Eat plenty of calcium-rich foods

like yogurt, spinach

,

and cheese."

Important Safety Information:

You should

not take BONIVA if you

have certain

problems with your esophagus

(the tube that connects your mouth and stomach), low blood calcium, cannot sit or stand for at least 60 minutes, have

severe kidney disease, or are allergic to BONIVA. Stop taking BONIVA and tell your doctor right aw ay if you experience

difficult or painful swallowing, chest pain, or severe or continuing heartburn, as these may be signs of serious upper

digestive problems. Follow the dosing instructions for once-monthly BONIVA carefully to lower the chance of these events

occurring. Side effects may include diarrhea, pain in the arms or legs, or upset stomach. Tell your doctor and dentist about

all the medicines you take. Tell them if you develop jaw problems (especially following a dental procedure) or severe bone,

joint, a n d /o r muscle pain. Your doctor may also recommend a calcium and vitamin D supplement.

You are encouraged to report negative side effects of prescription drugs to the FDA.

V isitwww.fda.gov/m edwatch, or call 1-800-FDA-1088.

*Bone density measured at the lumbar spine after 1

year of treatment. Individual results may vary.

‘ Bone density measured at the lumbar spine, total hip, or trochanter; 3 out of 4 at the femoral neck.

Please read Patient Information on the next page.

Enroll today. Call l-800-382-1517or

visit BONIVAfreetrial.com and try BONIVA free.

Genentech

A Member of the Roche Group

Help Stop and Reverse Bone Loss

BONIVA and symbol are trademarks of Roche Therapeutics Inc. © 2 0 1 0 Genentech USA, Inc. All rights reserved.

10297400